Gene that plays key role in cancer identified

Karolinska Institutet scientists have identified a gene that regulates the activity of another gene called p53, which protects against cancer. Writing about their work in the journal Molecular Cell, the researchers have revealed the newly identified gene as Wrap53.

Gene  p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously unknown gene,  Wrap53, controls the activity of p53. As the regulation mechanism is relatively unexplored, the study opens up new routes to solving the mystery of cancer.

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